Neuropeptide-processing enzymes: Applications for drug discovery
نویسندگان
چکیده
منابع مشابه
Targeting epigenetic enzymes for drug discovery.
Epigenetic control of gene transcription is the result of enzyme-mediated covalent modifications of promoter-region DNA sites and of histone proteins around which chromosomal DNA is wound. Many of the enzymes that mediate these epigenetic reactions are dysregulated in human diseases. Small molecule inhibitors against two classes of these enzymes have been approved for use in patients: DNA methy...
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ژورنال
عنوان ژورنال: The AAPS Journal
سال: 2005
ISSN: 1550-7416
DOI: 10.1208/aapsj070244